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What is Ferrous Bisglycinate or Iron Bisglycinate?
Ferrous Bisglycinate (iron bisglycinate, chelated iron or iron chelate) is an excellent alternative to restore normal levels of iron in the body, as it provides a source of highly bioavailable and stable iron and enables the concomitant administration of other minerals, reducing competition for the site of absorption and chelation by other constituents in the diet. In addition, it is a safe and effective alternative, as it significantly reduces the adverse effects in the stomach produced by its inorganic salts, what favours adherence to therapy.
Why is iron in the form of Bisglycinate more bioavailable?
Ferrous bisglycinate is a form of iron presented as a more beneficial alternative compared to other forms of iron traditionally used, such as iron sulphate, because iron bisglycinate offers greater bioavailability and better tolerance.
This is because bisglycinate is a chemical combination of iron with two molecules of the amino acid glycine, creating a protective field around iron against external agents, such as oxidation, absorption inhibitors or interactions with the gastrointestinal epithelium.
Refrances
- Ferrous bisglycinate as a source of iron for use in the manufacturing of foods and in food supplements. The EFSA Journal (2006) 299, 1-17.
- Layrisse, M. et al. Iron Bioavailability in Humans from Breakfasts Enriched with Iron Bis-Glycine Chelate, Phytates and Polyphenols. J. Nutr. 130: 2195–2199, 2000.
- Pineda, O. et al. Effectiveness of Treatment of Iron-Deficiency Anemia in Infants and Young Children with Ferrous Bis-glycinate Chelate. Nutrition 17:381–384, 2001
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