Mialtrim
Reactivate your musculoskeletal well-being
Unique combination of natural active ingredients for your muscles, bones and joints
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WHAT IS INFLAMMATION?
Inflammation or swelling is a process in tissues that consists of a series of cell and blood vessel phenomena with a defensive purpose against physical, chemical or biological aggressions, and which involves a significant energy expenditure. The inflammatory response is coordinated by an extensive device of elements that are organised into complex modulating and regulatory networks.
The stages are: heat, release of mediator molecules involved in the first line of defence; reddening, vascular alterations and chemotactic effects that attract more molecules and immune factors; pain or oedema due to the arrival of molecules and immune elements from blood, followed by the repair or series of processes leading to the total or partial reconstruction of the tissues damaged by the foreign agent or by the inflammatory response itself, to end up with the regulation of the inflammatory process.
The aim of controlling inflammation is somewhat paradoxical, first because the inflammatory response is necessary to enable the body to eliminate a foreign agent, and secondly because its modulation is highly important as, if not controlled, it causes important alterations not only to the directly affected structure, but to other adjacent structures or at a general level.
Reffrances
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2. Altman, R. D. et al. The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review. BMC Musculoskelet Disord. 2015.
3. Chang, Z. et al. Ascorbic acid provides protection for human chondrocytes against oxidative stress. Mol Med Rep. 2015.
4. Chin, K. Y. The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis. Drug Des Devel Ther. 2016.
5. Hall, A. J. et al. Safety, efficacy and anti-inflammatory activity of rho iso-alpha-acids from hops. Phytochemistry, 2008.
6. Jurenka, J. S. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev. 2009.
7. Marzocco, S. et al. Inhibition of inducible nitric oxide synthase expression by yuccaol C from Yucca schidigera roezl. Life Sci. 2004.
8. Oltean, H. et al. Herbal medicine for low-back pain. Cochrane Database of Systematic Reviews 2014.
9. Van Cleemput, M. et al. Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma. Mol Nutr Food Res. 2009
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